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CAS Number: 39924-52-2
5-dioxo-1-((6-(5-((3aS
and wound healing properties
JAK3-IN-1 possesses over 165-fold higher IC50s for BTK or ITK (IC50s = 794 and 1070 nM respectively)
is formed primarily from the breakdown of ceramide
O-1602 Catalog No.:M22717-C CAS Number: 39924-52-2O 1602 is an agonist of GPR55 (EC50 = 13 nM in a GTPS binding assay) and a derivative of the GPR55 agonist abnormal cannabidiol. It is selective for GPR55 over cannabinoid (CB) receptor 1 (CB1) and CB2 (EC50s = >30 M for both in GTPS binding assays). O 1602 (50 M) reduces growth of Mz ChA 1, HuCCT 1, CC LP 1, and SG231 cholangiocarcinoma cells and reduces tumor growth in a Mz ChA 1 mouse xenograft model when administered at a dose of 10 mg kg per day.